Methionine, vitamins B12 and B6
support methylation reactions critical for effective detoxification while methionine, vitamin B6 and artichoke help maintain healthy glutathione status.1 Additionally, as vitamin A precursors, the mixed carotenoids in this product, along with artichoke leaf extract, may induce sulfotransferase enzymes needed for detoxification.
Milk thistle (Silybum marianum)
one of the most well-researched protective herbs for hepatocytes and has even demonstrated the ability to promote the regeneration of liver cells in subjects with hepatitis and other liver disorders, possibly owing to increased hepatocyte protein synthesis.2,3 Milk thistle has also been shown to protect against liver cell injury from ethanol, acetaminophen, carbon tetrachloride or iron overload, and it inhibits the lipoxygenase enzyme, giving it antioxidant and anti-lipid peroxidation effects.3,4 Additional effects include aiding in bile flow, protecting against fibrosis, reducing the production of inflammatory cytokines, and potentially increasing insulin sensitivity.
Inositol
helps reduce the buildup of liver fat and expression of genes related to fatty acid synthesis. Along with inositol hexaphosphate, increases liver reduced glutathione levels and reduces liver triglyceride accumulation and serum alkaline phosphatase activity while significantly increasing hepatic superoxide dismutase and catalase activity, resulting in the preservation of liver cell integrity and improved antioxidant status.
Artichoke (Cynara scolymus)
has been found to enhance glutathione peroxidase activity and decrease production of reactive oxygen species.
Beetroot (Beta vulgaris)
s a valuable source of betaine (trimethylglycine), which can act to reduce fatty infiltration and degeneration of the liver, as well as help to thin the bile for improved gallbladder function.
Other Ingredients
Microcrystalline cellulose, cellulose (capsule), sunflower lecithin, vegetable stearate