Pure Oregano (120 ct)

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Oil of Oregano has powerful anti-yeast, anti-bacterial, and anti-viral properties, as well as intestinal cleansing benefits. It is often used with intestinal Candida/yeast, and as a first aid to help treat food poisoning. Oregano oil has also been found to have powerful antioxidant effects.

Oil of Oregano has powerful antioxidant and intestinal cleansing benefits.  It also helps to maintain a healthy microbial balance. The formula contains a 10:1 extract, which is the equivalent of 1,500 mg of oregano. 

Oil of Oregano is a powerful plant extract with highly effective antimicrobial properties, as well as important antioxidant and intestinal cleansing benefits. Similar to rosemary, garlic, ginger, turmeric, and other common herbs and spices, oregano is a familiar culinary ingredient whose potential pharmacologic role can be exploited when its essential components are isolated and provided in concentrated doses.

The oil extracts of Mediterranean oregano (Origanum vulgare) and other varieties have a history in botanical medicine for efficacy in the gastrointestinal tract as antimicrobial, antifungal, and antiparasitic agents.

Antimicrobial

The principal phenolic compounds in oregano—carvacrol [2-methyl-5-(1-methylethyl)phenol] and thymol (2-isopropyl-5- methylphenol)—are well known for their individual antibacterial properties, and when provided together as oregano oil, they have an additive effect.1,2 They have both been shown to be biocidal against strains of Staphylococcus, Listeria, Salmonella, and Clostridium.3 A study of two strains of Staphylococcus microorganisms in vitro showed oil of oregano to be highly effective in attenuating the growth of the Staph biofilm. The researchers proposed that the hydrophobic properties of carvacrol and thymol enabled them to interact with the lipid bilayer of bacterial cell membranes, “causing loss of integrity and leakage of cellular material such as ions, ATP and nucleic acids.”1 In the presence of these compounds, bacterial cells grew as looser colonies and the amount of biofilm was reduced in direct proportion to the dose of oregano extracts.

Antiparasitic

Oil of oregano has been shown to be a powerful antiparasitic. A small study involving 13 patients with three different intestinal parasites and complaints of GI distress and fatigue resulted in the complete eradication of parasites in 10 patients, along with amelioration of bloating, cramping, fatigue, and alternating diarrhea and constipation after 6 weeks of supplementation with 600 mg oil of oregano (200 mg t.i.d.). This powerful result was obtained with no other dietary or lifestyle modifications.11 A study investigating the antiparasitic properties of Mexican oregano showed it to be more effective against multiple strains of Giardia than the common antiparasitic drug, tinidazole. The mechanisms of action were similar to those observed in antibacterial studies: disruption of cell membranes leading to changes in osmotic balance, as well as irreversible damage to the anchor proteins of the nucleus.12

Why emulsify with olive oil?

Concentrated essential oils can be irritating to gastrointestinal mucosa. To avoid this, the oil of oregano in our product is emulsified in olive oil as a carrier. Additionally, emulsification increases the surface area of the essential oil particles, with one study estimating that 200 mg of oil could theoretically cover the entire luminal surface of the small intestine.11

References

1. Nostro A, Sudano Roccaro A, Bisignano G, Marino A, Cannatelli MA, Pizzimenti FC, Cioni PL, Procopio F, Blanco AR. Effects of oregano, carvacrol and thymol on Staphylococcus aureus and Staphylococcus epidermidis biofilms. J Med Microbiol. 2007 Apr;56(Pt 4):519-23.

2. Baser KH. Biological and pharmacological activities of carvacrol and carvacrol bearing essential oils. Curr Pharm Des. 2008;14(29):3106-19.

3. Fabian D, Sabol M, Domaracká K, Bujnáková D. Essential oils–their antimicrobial activity against Escherichia coli and effect on intestinal cell viability. Toxicol In Vitro. 2006 Dec;20(8):1435-45.

4. Lambert RJ, Skandamis PN, Coote PJ, Nychas GJ. A study of the minimum inhibitory concentration and mode of action of oregano essential oil, thymol and carvacrol. J Appl Microbiol. 2001 Sep;91(3):453-62.

5. Alexopoulos A, Kimbaris AC, Plessas S, Mantzourani I, Theodoridou I, Stavropoulou E, Polissiou MG, Bezirtzoglou E. Antibacterial activities of essential oils from eight Greek aromatic plants against clinical isolates of Staphylococcus aureus. Anaerobe. 2011 Dec;17(6):399-402.

6. Nostro A, Blanco AR, Cannatelli MA, Enea V, Flamini G, Morelli I, Sudano Roccaro A, Alonzo V. Susceptibility of methicillin-resistant staphylococci to oregano essential oil, carvacrol and thymol. FEMS Microbiol Lett. 2004 Jan 30;230(2):191-5.

7. Adam K, Sivropoulou A, Kokkini S, Lanaras T, Arsenakis M. Antifungal Activities of Origanum vulgare subsp. hirtum, Mentha spicata, Lavandula angustifolia, and Salvia fruticosa Essential Oils against Human Pathogenic Fungi. J. Agric. Food Chem. 1998, 46, 1739−1745.

8. Giordani R, Regli P, Kaloustian J, Mikaïl C, Abou L, Portugal H. Antifungal effect of various essential oils against Candida albicans. Potentiation of antifungal action of amphotericin B by essential oil from Thymus vulgaris. Phytother Res. 2004 Dec;18(12):990-5.

9. Chami N, Bennis S, Chami F, Aboussekhra A, Remmal A. Study of anticandidal activity of carvacrol and eugenol in vitro and in vivo. Oral Microbiol Immunol. 2005 Apr;20(2):106-11.

10. Chami F, Chami N, Bennis S, Trouillas J, Remmal A. Evaluation of carvacrol and eugenol as prophylaxis and treatment of vaginal candidiasis in an immunosuppressed rat model. J Antimicrob Chemother. 2004 Nov;54(5):909-14.

11. Force M, Sparks WS, Ronzio RA. Inhibition of enteric parasites by emulsified oil of oregano in vivo. Phytother Res. 2000 May;14(3):213-4. 12.Ponce-Macotela M, Rufino-González Y, González-Maciel A, Reynoso-Robles R, Martínez-Gordillo MN. Oregano (Lippia spp.) kills Giardia intestinalis trophozoites in vitro: antigiardiasic activity and ultrastructural damage. Parasitol Res. 2006 May;98(6):557-60.