We use the unique, patented, chelated mineral Magtein™ which contains magnesium L-threonate.
This is a superior form of magnesium capable of delivering magnesium across the blood-brain barrier.
Researchers at MIT concluded that elevating brain magnesium content via supplementation with Magtein™ may be a useful strategy to support cognitive function and decrease age-related memory decline.
Several studies indicate that connections in the brain's hippocampus, a critical region in the brain associated with learning and memory, especially short-term to long-term memory conversion, deteriorate during chronic stress. Cortisol bathes the cells of the hippocampus causing destruction. With a form of magnesium that can cross the blood-brain barrier, we can transport magnesium ions to those brain cells.
Magnesium deficiency is an extremely common condition that affects the majority of the population. Magnesium has been removed from most water supplies, soil degradation and mineral depletion due to the consumption of flour, wheat and other grains, combined with a lack of adequate dietary magnesium creates the perfect storm for this mineral to be in short supply.
Magnesium is dumped from the kidneys during stress, especially in adrenal fatigue and is aggravated by sweating, alcohol consumption and many medications.
Magnesium helps to regulate neuronal nitric oxide production in which a deficiency could cause neuronal damage that could manifest as memory loss, depression, anxiety, ADHD, sleep issues, inability to relax and poor cognition
Anxiety disorders affect an estimated 20 million Americans. Many go undiagnosed and continue to suffer from this mental disorder.
Magnesium L-threonate enhances synaptic plasticity in the hippocampus which enhances the extinction of fear memory and improves overall memory function. Studies have found low levels of magnesium in the brains of patients suffering from Alzheimer's disease. Increasing plasticity in the amygdala, the fear center of the brain is crucial to coping with the incessant stressors of the modern world.
- Age-related memory decline (Alzheimer’s disease)
- Post traumatic stress disorder
- 2 grams for maintenance
- 3-4 grams for those with memory loss or recognition difficulties
- For best results, take Calm Clarity in divided doses
- Consider combining with Neuro Synergy
Effects of elevation of brain magnesium on fear conditioning, fear extinction, and synaptic plasticity in the infralimbic prefrontal cortex and lateral amygdala. Abumaria N, et al. J Neurosci. 2011 Oct 19;31(42):14871-1.
Kalzium ist nicht alles. Bush AI. Neuron. 2010 Jan 28;65(2):143-4.
Enhancement of learning and memory by elevating brain magnesium. Slutsky I, et al. Neuron. 2010 Jan 28;65(2):165-77.
The role of the medial prefrontal cortex-amygdala circuit in stress effects on the extinction of fear. Akirav I, Maroun M. Neural Plast. 2007; 2007:30873. Epub 2007 Jan 16.